You don't understand what I mean Joe. Adding a website to your antivirus' trusted sites list means it will not scan any incoming traffic from that website.
You are talking about your antivirus running scheduled scans of the files on your PC whilst playing the game. If that is happening you just need to reschedule the scans, and disabling your antivirus at any time whilst connected to the internet is just plain daft!
Scott, most all antivirus programs today, unless you have turned it off, by default are scanning your computer all the time, in the background. A scheduled task would be to do a complete scan of your computer, starting at a specific time and day. You also have the option of turning off the animation of your virus icon while it is scanning.
But most all are running scans in the background from the time your computer starts. Not talking about scanning incoming files from the internet, but the files that are on your computer. Check your options.