I am not so sure as to "[C]ams tend to lie" but your shot (direction) will differ depending upon what camera angle your are on when you hit. Further, certain shots play truer depending on the camera you use (for example, on flops shots using reverse cam works best and remember to aim left of pin as flops fly left to right).
As for changes in wind direction, as in real world, winds can come from slightly different directions depending upon location and elevation. A certain 3 par on Wolf Creek always moves the ball severely to left no matter what wind is, because you are hitting down into a canyon green and this has an effect on the wind...it makes it "swirl" in a circular direction. Same on holes on Pebble that the greens are exposed to the ocean winds...all this effects flight as in real world.
What I suggest is, on approach shots, check the cam on the green and compare the wind direction from that on the tee, or you fairway lie, often times you will see that the wind over the green is different from where you are hitting from and then you can adjust accordingly.
I am no expert but the above seems to be what I have observed.